Brain Tumors Research Today is a free monthly online journal that collates and summarizes the latest research about Brain Tumors, including details on symptoms, benign and malignant tumors, gliomas, screening, treatment.

Secondary glioblastoma multiforme after treatment for primary choroid plexus carcinoma in childhood.

Postovsky S, Vlodavsky E, Eran A, Guilburd J, Ben Arush MW

Department of Pediatric Hematology-Oncology, Meyer Children's Hospital, Technion-Israel Institute of Technology, Haifa, Israel. s_postovsky@rambam.health.gov.il

A 15-year-old boy was diagnosed with choroid plexus carcinoma (CPC) of the right lateral ventricle. His metastatic work-up was negative. After complete macroscopic resection of the tumor, the patient was treated with chemotherapy consisting of vincristine, cisplatin, etoposide, and carboplatin, followed by radiotherapy for a total dose of 34.2 Gy on the whole craniospinal axis plus a boost of 19.8 Gy at the tumor region. The patient remained in complete clinical and radiologic remission over the next 5 years when a secondary malignant tumor, glioblastoma multiforme, a rare complication of the treatment of CPC, was diagnosed. This case reflects the necessity of thorough follow-up in long-term survivors of CPC.

Published 6 April 2007 in J Pediatr Hematol Oncol, 29(4): 248-52.
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